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Malignant melanoma is the second most common vulvar malignancy which occurs in elderly females. In advanced stages of the disease, distant metastases can occur to any organ; hence, comprehensive radiological evaluation is necessary. We report a case of a 45-year-old female who presented with progressively increasing growth over the vulva for 6 months. On detailed clinical, pathological, and radiological workup, multiple metastases were found in the brain, liver, pancreas, peritoneum, lungs, and pleura. The final diagnosis of vulvar melanoma with multisystemic metastases was made after the histopathological examination
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Background:A surge of mucormycosis during the second wave of COVID intrigued the doctors in India to look for the epidemiology of the illness.Diabetes is the most common risk factor for mucormycosis.COVID can cause hyperglycemia due to various reasons.In this study,we describe the outcome of post COVID mucormycosis with respect to the glycemic status of the patient. (1)To describe the glycemic parameters of patients with COVID-19 Associated M Objectives: ucormycosis.(2)To describe the one month outcome of the patients.(3)To compare patients with Newly Diagnosed Diabetes Mellitus Post COVID-19 and patients having preexisting diabetes mellitus. 75 patients with probable or proven mucormycosis wit Methodology: h history of COVID atleast 2 weeks before were randomly selected from the mucor ward of Rajiv Gandhi Government General Hospital and their glycemic profile assessed.They were followed up for one month and the results were statistically analyzed. Regarding the prior CO Results: VID illness,patients had a median hospital stay of 7 days,received 5 days of intravenous steroids and 3.48 days of supplemental oxygen.Patients who had hyperglycemia during COVID also had statistically significantly higher iv steroid use and higher need for oxygen.There was a statistically very significant(p<0.001) increase in the number of diabetics post COVID(from 57.3% prior to COVID to 90.7% post COVID).Majority of the Mucormycosis patients(69.3%) had severe hyperglycemia during presentation.Pre-existing diabetics had a statistically significant higher incidence of sepsis and renal failure during treatment for mucormycosis.Otherwise,there was no significant difference in outcome between various grades of severity of hyperglycemia,and no distinction was found between pre-existing diabetics and newly diagnosed diabetics
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Acinic cell carcinoma (ACC) is a low-grade malignant salivary gland neoplasm that comprises approximately 17% of primary salivary gland malignancies or about 6% of all salivary gland neoplasms. The most common intraoral sites are the buccal mucosa, lips, and palate. The diagnosis of ACC frequently presents difficulties, owing to its great radiological and cytological similarity with benign tumors and with normal acinar component of the salivary gland, respectively. The management of ACC consists of complete surgical excision. Here, we report a case of ACC on the left retromolar trigone, a rare location in a 44-year-old female
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Background: Hysterectomy is one of the most common gynecological surgeries performed around the world. This study was done to review the data of all patients who underwent TLH. With this study a uniform method of performing TLH by a single surgeon was assessed.Methods: A 5 years retrospective study was performed at Sri Dharmasthala Manjunatheshwara College of Medical Sciences and Hospital Dharwad, Karnataka India. Demographic data, pre-operative findings, indication for surgery, intra-operative and post-operative complications, duration of surgery were recorded and analyzed.Results: A total of 118 women were included in the study. Mean age of the patients wasMost common indication for the surgery was leiomyoma. Mean operating time was 162.18 minutes. Mean weight of the post-operative specimen was 208.45 grams. Intra-operative urinary bladder injury was seen in 1 patient. Conversion to laparotomy was needed in 2 patients.Conclusions: With improving experience TLH can be performed safely without complications. As number of surgeries done increases duration of TLH reduces. TLH can be effectively used to avoid laparotomy.
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Chronic sinusitis, defined as an inflammatory process that involves the paranasal sinuses and persists for 12 weeks or longer. The conventional treatment is either conservative or surgical. Since this ailment is of a chronic nature, simple conservative management will not be sufficient for a cure. Even though the surgery is effective, there is chance of recurrence and morbidity. The clinical picture of chronic sinusitis shows the predominance of Kaphavata dosha in Jatrurdhwa. Sigru is a single drug having Thikshna ushna guna and Vatakaphahara properties and is included in Sirovirechana group. Arkaprakasa written by Ravana illustrates a large number of Arkas (distillates) which is found to be very effective and harmless and Sigrubeeja Arka nasya indicated in Siroroga was selected for the study. Methods: The study design was interventional pre and post evaluation without control and sample size fixed as 30 patients. The data collection was done with case proforma, symptomatic scoring using VAS scale, Nasal Signs and Symptoms Score (NSSS), and X-ray PNS. Selected patients were subjected to Nasyakarma with Sigrubeeja arka for a period of 7 days. Assessments were done prior to the commencement of intervention and on 15th, 30th, 60th day of follow up. Statistical analysis was done using Wilcoxon Signed Rank test. Result: Change in outcome variables like headache, nasal obstruction, nasal discharge, loss of smell, and postnasal drip, showed significant results. Conclusion: Sigrubeejaarka was found to be effective in chronic sinusitis.
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Background: Anemia due to Iron deficiency is the commonest malnutrition disorder seen throughout the world and in India. It is also responsible for increased incidence of premature births, low birth weight babies and high perinatal mortality. Hence, the present study undertaken to assess efficacy and safety of injectable iron sucrose with oral ferrous ascorbate.Methods: 100 pregnant women, between gestational age 14 and 28 weeks were divided randomly into two groups i.e. group A consists of oral iron, a total of 200 mg of elemental iron per day, two 100mg iron tablets per day and group B consists of iron sucrose at the rate of 200mg on alternate OPD day. Informed consent was taken from each patient.Results: The percentage rise in hemoglobin at fourth and eighth weeks of treatment was statistically significant when compared to the baseline. Statistically significant rise in hemoglobin, PCV and ferritin levels were found at fourth and eighth weeks in IV group when compared to oral group.Conclusions: This study concluded that intravenous iron sucrose is safe and highly efficacious for the treatment of anemia in pregnancy. It restores iron stores more promptly. Iron sucrose therapy is more effective in achieving the optimum results, an increase in hemoglobin concentration, PCV levels and an increase in ferritin levels also. Therefore, it is a suitable alternative to oral iron with minimal side effects in those patients who cannot tolerate oral iron therapy.
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Background Ischemic heart disease (IHD) and chronic airway disease (COPD and Asthma) are major epidemics accounting for significant mortality and morbidity. The combination presents many diagnostic challenges. Clinical symptoms and signs frequently overlap. There is a need for airway evaluation in these patients to plan appropriate management. Methods Consecutive stable IHD patients attending the cardiology OPD in a tertiary care centre were interviewed for collecting basic demographic information, brief medical, occupational, personal history and risk factors for coronary artery disease and airway disease, modified medical research centre (MMRC) grade for dyspnea, quality of life-St. George respiratory questionnaire (SGRQ), spirometry and six-min walk tests. Patients with chronic airway obstruction were treated as per guidelines and were followed up at 3rd month with spirometry, six-minute walk test and SGRQ. Results One hundred fourteen consecutive patients with stable cardiac disease were included (Males-88, Females-26). Mean age was 58.89 ± 12.24 years, 53.50% were smokers, 31.56% were alcoholics, 40.35% diabetics, 47.36% hypertensive. Twenty five patients had airway obstruction on spirometry (COPD-13 and Asthma-12) and none were on treatment. Thirty-one patients had cough and 48 patients had dyspnea. Patients with abnormal spirometry had higher symptoms, lower exercise tolerance and quality of life. Treatment with appropriate respiratory medications resulted in increase in lung function, quality of life and exercise tolerance at 3rd month. Conclusion Chronic respiratory disease in patients with stable IHD is frequent but often missed due to overlap of symptoms. Spirometry is a simple tool to recognize the underlying pulmonary condition and patients respond favorably with appropriate treatment
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We assessed the relationship between parental and socioeconomic characteristics and nutritional status of children under 5 years in Egypt. Data from the 2000 Egypt Demographic and Health Survey were used. A logistic regression technique was used to estimate the odds of being malnourished. Children whose mothers had a higher level of education and were > 150 cm had a lower risk of stunting than those of mothers with no education and shorter height [< 150 cm]. Parental consanguinity, rural residence, high birth order and short birth interval significantly increased the odds of stunting. Children aged >/= 12 months had greater odds of stunting than those < 12 months